Journal of Complementary and Alternative Medical Research 2019-12-15T09:44:10+00:00 Journal of Complementary and Alternative Medical Research Open Journal Systems <p style="text-align: justify;"><strong>Journal of Complementary and Alternative Medical Research (ISSN: 2456-6276)</strong> aims to publish high quality papers (<a href="/index.php/JOCAMR/general-guideline-for-authors">Click here for Types of paper</a>) in the areas of Complementary, Alternative and Integrative medical research. This journal facilitates the research and wishes to publish papers as long as they are technically correct, scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.</p> Validation of Siddha Diagnostic Procedure of Manikkadai nool for Gunmam Patients at Government Siddha Medical College & Hospital, Palayamkottai 2019-12-15T09:44:10+00:00 Rakulini Raveendran A. Rajarajeshwari S. Victoria <p><strong>Introduction: </strong>Siddha Medicine is a system of traditional medicine originating in ancient Tamil Nadu in South India and Sri Lanka. Traditionally, it is taught that the <em>siddhas</em> laid the foundation for this system of medicine. Siddha system has a unique diagnostic method to identify the diseases and their causes. <em>Manikkadai Nool</em> is one of the diagnostic tool. It is explained in the <em>Agasthiyar Soodamani Kajiru Soothiram </em>by Saint Veadammamuni in <em>Pathinen Siddhar Naadi Nool</em>.</p> <p><strong>Aim: </strong>The primary aim of this study was to validate the Siddha diagnostic procedure of <em>Manikkadai nool</em> for <em>gunmam patients.</em></p> <p><strong>Study Setting: </strong>Government Siddha Medical College, Palayamkottai from April to August 2019.</p> <p><strong>Methodology:</strong> It is an observational study<em>. </em>After identifying the eligible subjects, Data will be collected by using the interview administrated questionnaire &amp; relevant data will be collected by measurement. Collected data were processed and statistically analysed by a simple statistical method using Microsoft Excel.</p> <p><strong>Results and Discussion:</strong> <em>Gunmam</em> symptoms are included in 10, 9 ½, 8 ¾, 8, 7 ½, 7, 6 ½ &amp; 6 ¼ <em>Manikkadai </em>measurements according to the siddha literatures. Researcher has been divided the <em>gunmam </em>conditions as mild moderate and severe condition according to the evidence of literatures, Researcher has been included Premonitory symptoms as Mild Condition, Common signs and symptoms as Moderate Condition and complications as Severe condition. Mild condition is in 10-9 fbs <em>Manikkadai </em>measurements. Moderate condition is in 8 ¾-7 ¾ fbs <em>Manikkadai </em>measurements. Severe condition is in 7 ½-6 ½ &gt; <em>Manikkadai </em>measurements. 55% (11) of right hand <em>Manikkadai </em>measurements in male and 53% (16) of Right hand <em>Manikkadai </em>measurements in female have been correlated with the siddha literatures in the diagnosis of <em>gunmam</em>. Pearson correlation value implies that negative correlation between the chronicity of <em>gunmam </em>and <em>Manikkadai </em>measurement. This data showed the negative relationship between the severity of <em>gunmam, </em>&amp; <em>manikkada</em>i measurements.</p> <p><strong>Conclusion: </strong>Majority of the<em> gunmam </em>subjects were females (60%). The maximum number of subjects was observed in Pitha Kaalam. Majority of the <em>gunmam </em>subjects had <em>vali azhal naadi </em>(38%) and <em>azhal vali naadi </em>(32%). Nei kuri was observed as vali azhal &amp; azhal vali in <em>gunmam </em>subjects. Siddha Physicians could be diagnosed the <em>gunmam </em>fifty percentage with the help of <em>Manikkadai </em>measurements. Pearson correlation value implies that negative correlation between the chronicity of <em>gunmam </em>and <em>Manikkadai </em>measurement. This data showed the negative relationship between the severity of <em>gunmam </em>&amp; <em>manikkada</em>i measurements. Out of 50 <em>gunmam </em>subjects, 45 were in the assumed assessment criteria range. So further study is essential to validate this assumed assessment of criteria of <em>manikkadai </em>measurement in diagnosis of <em>gunmam.</em></p> 2019-12-02T00:00:00+00:00 ##submission.copyrightStatement## Effect of Ethanolic Extract of Trigonella foenum-graecum L. Seeds on Reproductive System of Male Albino Rats 2019-12-15T09:44:09+00:00 Madhulika Singh G. N. Verma <p><strong>Aims:</strong> The present study was undertaken to assess the antispermatogenic and antifertility efficacy of ethanolic extract of <em>Trigonella foenum-greacum </em>seeds.</p> <p><strong>Methodology:</strong> Aqueous solution of the extract (250 mg/kg b.wt/day) when administered orally for 45 days to adult male albino rat (Duckray strain).</p> <p><strong>Results:</strong> Seeds extract caused inhibition of spermatogenesis as well as inability to mate with normal untreated female rats of proven fertility. There occurred a significant decrease in absolute and relative weights of testis and seminal vesicle and increase in epididymal weight, whereas of ventral prostate and coagulating gland remained unchanged. Sperm concentration and motility in the cauda epididymis was also decreased. Increased incidence of separation of head and tail pieces of spermatozoa was seen in the epididymal smear. Histologically, testis of experimental animals showed arrest of spermatogenesis at the secondary spermatocytes stage and there was deposition of cellular debris in semineferous tubular lumen. The spermatids were not properly developed and interstitial cells were very sparse and degenerated. However, there was no evidence of damage to the spermatogonia. Oral treatment of extract did not affect the body weight of animals. Quantitative estimation of marker testicular enzymes, e.g., sorbitol dehydrogenase showed a significant decrease whereas lactate dehydrogenase and gamma-glutamyl transpeptidase levels were significantly increased.</p> <p><strong>In conclusion:</strong> These results suggest that <em>T. foenum-greacum</em>, may induce male infertility in rats, therefore, should be considered further as a potential male antifertility agent.</p> 2019-12-09T00:00:00+00:00 ##submission.copyrightStatement##